GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| UCEC | cis | rs950169 | 1 | rs1848093 | chr15:84755527 | LOC388152 | chr15:84867600-84898920:- | -0.47 | -4.83 | 3.25E-6 | Schizophrenia |
| UCEC | cis | rs1577917 | 1 | rs1857964 | chr6:86635994 | SNHG5 | chr6:86386726-86388451:- | -0.45 | -5.39 | 2.62E-7 | Response to antipsychotic treatment |
| UCEC | cis | rs1577917 | 1 | rs1857965 | chr6:86630776 | SNHG5 | chr6:86386726-86388451:- | -0.42 | -4.96 | 1.9E-6 | Response to antipsychotic treatment |
| UCEC | cis | rs10461617 | 1 | rs1862619 | chr5:56098256 | C5orf35 | chr5:56205103-56213010:+ | 0.47 | 5.58 | 1.06E-7 | Type 2 diabetes |
| UCEC | cis | rs10935120 | 1 | rs1863913 | chr3:134200205 | ANAPC13 | chr3:134196547-134204865:- | 0.39 | 4.46 | 1.59E-5 | Height |
| UCEC | cis | rs10935120 | 1 | rs1874883 | chr3:134205071 | ANAPC13 | chr3:134196547-134204865:- | 0.43 | 4.89 | 2.54E-6 | Height |
| UCEC | cis | rs703842 | 1 | rs1875124 | chr12:58196802 | TSFM | chr12:58176536-58191367:+ | -0.45 | -4.76 | 4.48E-6 | Multiple sclerosis |
| UCEC | cis | rs9309473 | 1 | rs1881245 | chr2:73649928 | ALMS1P | chr2:73872046-73912692:+ | 0.51 | 5.93 | 1.97E-8 | Metabolite levels |
| UCEC | cis | rs10461617 | 1 | rs190414 | chr5:56116772 | C5orf35 | chr5:56205103-56213010:+ | 0.55 | 5.94 | 1.83E-8 | Type 2 diabetes |
| UCEC | cis | rs950169 | 1 | rs1911155 | chr15:84787635 | LOC388152 | chr15:84867600-84898920:- | -0.45 | -4.63 | 7.77E-6 | Schizophrenia |
| UCEC | cis | rs1577917 | 1 | rs1911552 | chr6:86638024 | SNHG5 | chr6:86386726-86388451:- | -0.46 | -5.96 | 1.65E-8 | Response to antipsychotic treatment |
| UCEC | cis | rs1577917 | 1 | rs1911553 | chr6:86630892 | SNHG5 | chr6:86386726-86388451:- | -0.45 | -5.37 | 2.92E-7 | Response to antipsychotic treatment |
| UCEC | cis | rs1577917 | 1 | rs1962716 | chr6:86648436 | SNHG5 | chr6:86386726-86388451:- | -0.51 | -5.79 | 3.98E-8 | Response to antipsychotic treatment |
| UCEC | cis | rs41266839 | 1 | rs1979 | chr6:26377591 | BTN3A2 | chr6:26365398-26378546:+ | -1.01 | -6.44 | 1.47E-9 | Schizophrenia |
| UCEC | cis | rs199347 | 1 | rs199347 | chr7:23293746 | GPNMB | chr7:23286316-23314728:+ | -0.41 | -4.83 | 3.3E-6 | Parkinson's disease |